Slug Products

Description

SLUG encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Bioinformatics

Entrez	20583 Mouse 6591 Human
Uniprot	AAH14890 Human NM_003068 Human NP_003059 Human NP_003059.1 Human O43623 Human
Product By Gene ID	6591
Alternate Names	MGC10182 Neural crest transcription factor Slug Protein snail homolog 2 slug homolog, zinc finger protein (chicken) SLUGH SLUGzinc finger protein snail 2 snail homolog 2 (Drosophila) WS2D zinc finger protein SNAI2

Research Areas for Slug

Find related products by research area and learn more about each of the different research areas below.

Neuronal Cell Markers
Neuronal Stem Cell Markers
Phospho-Specific

Related Slug Blog Posts

Check out the latest blog posts on Slug.

Epithelial-Mesenchymal Transition (EMT) Markers Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...    Read more.

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CD63: is it pro-metastatic or anti-metastatic? CD63 is a type II membrane protein belonging to tetraspanin superfamily and it play key roles in the activation of several cellular signaling cascades along with acting as TIMP1 receptor. It is expressed by activated platelets, monocytes,...    Read more.

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