Species: Hu, Mu, Rt, Bv, Ch, Pm, Sh
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bv, Ca
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Sin1 is a novel component of the eukaryotic SAPK pathway. Sin1 and the H3 and H4 histones interact genetically, with the C terminus of Sin1 physically associating with components of the SWI-SNF complex. This interaction is blocked by the N-terminal half of the protein in full length Sin1. It has been proposed that Sin1 acts as a regulatable bridge between the SWI-SNF complex and the nucleosome Sin1 is also required for effective transcription via the AP-1 factor Pap1, but does not prevent its nuclear translocation. Sin1 is a novel component of the eukaryotic SAPK pathway.
Bioinformatics
Entrez |
Mouse Rat Human |
Uniprot |
Human Human Human Human Human Human Human Human Human Human Human Human |
Product By Gene ID |
79109 |
Alternate Names |
- JC310
- MEKK2-interacting protein 1
- MGC2745
- MIP1SIN1SIN1b
- Mitogen-activated protein kinase 2-associated protein 1
- mitogen-activated protein kinase associated protein 1
- mSIN1
- ras inhibitor MGC2745
- SAPK-interacting protein 1
- SIN1g
- stress-activated map kinase interacting protein 1
- Stress-activated map kinase-interacting protein 1
- stress-activated protein kinase-interacting 1
- target of rapamycin complex 2 subunit MAPKAP1
- TORC2 subunit MAPKAP1
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