SF3B2 Products

Description

SF3B2 encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.

Bioinformatics

Entrez	10992 Human 293671 Rat 319322 Mouse
Uniprot	AAH07610 Human AAH07610.1 Human NP_006833 Human Q13435 Human
Product By Gene ID	10992
Alternate Names	Cus1 pre-mRNA splicing factor SF3b 145 kDa subunit Pre-mRNA-splicing factor SF3b 145 kDa subunit SAP145SAP 145 SF3b1 SF3B145 SF3b145 SF3b150 spliceosome associated protein 145 Spliceosome-associated protein 145 splicing factor 3B subunit 2 splicing factor 3b, subunit 2, 145kD splicing factor 3b, subunit 2, 145kDa