Species: Hu, Mu, Rt
Applications: WB, IHC, ChIP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: PAGE
Description
Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Histone methyltransferases (HMTases) selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. Set7/9 is a histone specific HMTase that methylates histone H3 lysine 4. Set7/9 transfers methyl groups to lysine 4 of histone H3 in complex with S-adenosyl-L-methionine. Human Set7/9 is a 336 amino acid protein.
Bioinformatics
| Entrez |
Rat
Mouse
|
| Uniprot |
Human
|
| Product By Gene ID |
80854 |
| Alternate Names |
- EC 2.1.1.43
- H3-K4-HMTase SETD7
- histone H3-lysine 4-specific methyltransferase
- histone-lysine N-methyltransferase SETD7
- KIAA1717SET domain-containing protein 7
- KMT7FLJ21193
- Lysine N-methyltransferase 7
- SET domain containing (lysine methyltransferase) 7
- SET7/9Histone H3-K4 methyltransferase SETD7
- SET7Set9
- SET9
|
