Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
POLE4, also known as DNA polymerase epsilon subunit 4, is 117 amino acids long and approximately 12kDa. POLE4 localizes to the nucleus. POLE, POLE2, POLE3 and POLE4 are elements of the epsilon DNA polymerase complex (Pol epsilon), and as such, POLE4 plays a role in the process of nuclear DNA replication. POLE4 interacts with POLE, POLE2, and POLE3, as well as UBE3A and HSPA13. POLE4 is implicated in a variety of pathways including the DNA replication pathway, Nucleotide excision repair, Purine metabolism, and cell cycle control of chromosomal replication.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
56655 |
Alternate Names |
- DNA polymerase epsilon p12 subunit
- DNA polymerase epsilon subunit 4
- DNA polymerase epsilon subunit p12
- DNA polymerase II subunit 4
- EC 2.7.7.7
- p12
- polymerase (DNA-directed), epsilon 4 (p12 subunit)
- YHHQ1
|
Research Areas for POLE4
Find related products by research area and learn more about each of the different research areas below.
DNA PolymerasesDNA Repair