Pea3 Products

Description

Pea3, also known as ETS translocation variant 4, is an approximately 54 kDa, 484 amino acid protein, which is involved in transcriptional activation of adenovirus E1A gene, and is regulated by ERBB2, STK11, PLAG1, CTNNB1. Studies about the Pea3 protein are being done on diseases such as ovaria, pancreatic, gastric, breast, and prostate cancers. As well as peripheral primitive neuroectodermal tumors, carcinoma, adenoma, ewings sarcoma, squamous cell carcinoma, and oral cancers. The Pea3 protein has shown interaction with Taf7, EP300, SRF, HOXD4, STK11, and involvement in the ErbB2-ErbB3 Heterodimer pathway.

Bioinformatics

Uniprot	NM_001079675 Human P43268 Human
Product By Gene ID	2118
Alternate Names	Adenovirus E1A enhancer-binding protein E1A-FE1A enhancer binding protein E1AFETS translocation variant 4 ets variant 4 ets variant gene 4 (E1A enhancer binding protein, E1AF) ets variant gene 4 (E1A enhancer-binding protein, E1AF) EWS protein/E1A enhancer binding protein chimera PEA3 PEAS3 Polyomavirus enhancer activator 3 homolog polyomavirus enhancer activator-3 Protein PEA3

Research Areas for Pea3

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Cancer