Species: Hu
Applications: WB, Simple Western, Flow, ICC/IF
Host: Sheep Polyclonal
Species: Hu, Mu, Rt, Fi, Pm, Pm, Sh
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Rb, RM, Xp
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
PAX genes encode nuclear transcription factors which are regarded as major controllers of developmental processes in both vertebrates and invertebrates. Mutations in murine PAX genes underlie three natural mouse alleles and several corresponding human syndromes (aniridia, foveal hypoplasia and Peters® anomaly). Murine PAX genes have been shown to be proto-oncogenes. Furthermore, human PAX genes have recently been demonstrated to play an influential part in some common human cancers such as brain tumors and lymphomas. All PAX genes encode a DNA-binding domain termed the paired domain and in addition some also encode a second binding domain--the paired type homeobox. PAX6 is involved in the early development of the optical vesicle and has been shown to interact with Six3, another important visual development protein.
Bioinformatics
| Uniprot |
Human
Human
Human
Human
Rat
|
| Product By Gene ID |
5080 |
| Alternate Names |
- keratitis)
- MGC17209
- Oculorhombin
- paired box 6
- paired box protein Pax-6
|
![Western Blot Pax6 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Pax6_AF8150_Western_Blot_14743.jpg)
![Immunocytochemistry Pax6 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Pax6_AF8150_Immunocytochemistry_14427.jpg)
![Simple Western Pax6 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Pax6_AF8150_Simple_Western_17126.jpg)
![Intracellular Staining by Flow Cytometry Pax6 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/af8150_human-pax6-affinity-purified-polyclonal-ab-flow-cytometry-3011202315350.jpg)
