PARP4 Products

Description

PARP4 encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq]

Bioinformatics

Uniprot	NP_006428 Human NP_006428.2 Human Q9UKK3 Human
Product By Gene ID	143
Alternate Names	193 kDa vault protein ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1 ADPRTL1I-alpha-I-related EC 2.4.2.30 H5 proline-rich p193 PARP-4 PARPL PARP-related PARP-related/IalphaI-related H5/proline-rich PH5P poly (ADP-ribose) polymerase family, member 4 poly [ADP-ribose] polymerase 4 poly(ADP-ribose) synthetase poly(ADP-ribosyl)transferase-like 1 Vault poly(ADP-ribose) polymerase vault protein, 193-kDa VAULT3 von Willebrand factor A domain containing 5C VPARPKIAA0177 VWA5C

Research Areas for PARP4

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Repair
Hypoxia