PAK1 Products

Description

p21-activated kinase 1 (PAK1) is a member of a family of serine/threonine protein kinase defined by their interaction with the small GTPases, Cdc42 and Rac (1-2). The PAK proteins can be essentially divided into two categories, groups I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK5 and PAK6), based on their structures (3). PAK1 participates in regulating the actin cytoskeleton, focal adhesion contacts, cell motility, apoptosis and transcription. It also promotes the disassembly of stress fibers (4-5). PAK1 also binds PIX (PAK-binding protein), COOL and adapter protein Nck (5).

Bioinformatics

Uniprot	NM_001105663 Human NM_002576 Human NP_001122092 Human NP_002567 Human NP_002567 Human NP_002567.3 Human Q13153 Human Q13153 Human
Product By Gene ID	5058
Alternate Names	Alpha-PAK alpha-PAK EC 2.7.11 EC 2.7.11.1 MGC130000 MGC130001 p21 protein (Cdc42/Rac)-activated kinase 1 p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) p21-activated kinase 1 p65-PAK PAK-1 PAKalpha serine/threonine-protein kinase PAK 1 STE20 homolog, yeast

Research Areas for PAK1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Breast Cancer
Cancer
Neuroscience
Phospho-Specific
Signal Transduction

Related PAK1 Blog Posts

Check out the latest blog posts on PAK1.

Myosin is More than Just a Heavy Lifter Myosin is a well-known, hexameric molecular motor that is a key cytoskeletal component. It consists of a pair of myosin heavy chain subunits (MHC), a pair of essential myosin light chain subunits (MLC), and a pair of regulatory light chain subunits (R...    Read more.

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