Species: Hu, Mu, Rt, Fe
Applications: WB, ICC/IF, IHC, KO
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ch
Applications: Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Nkx2.2, or Homeobox protein Nkx-2.2, consists of a 273 amino acid isoform that is 30 kDa, and is involved in controlling and maintaining the expression of genes within pancreatic endocrine cells and axons. Current research is being conducted on the relationship between Nkx2.2 and a variety of diseases and disorders, including glioma, neuronitis, maturity-onset diabetes, pancreatitis, Partington syndrome, sarcoma, gastrointestinal neuroendocrine tumor, acute lymphoblastic leukemia, multiple sclerosis, and carcinoid tumors. The protein has been linked to the Wnt, Hedgehog, and notch pathways, as well as regulation of beta-cell development and gene expression. NKx2.2 interacts with several other proteins, including OLIG2, HDAC1, SIN3A, FOXA2, and FOXO1.
Bioinformatics
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
4821 |
| Alternate Names |
- Homeobox protein NK-2 homolog B
- NK-2 (Drosophila) homolog B
- NK2 homeobox 2
- NK2 transcription factor related, locus 2 (Drosophila)
- NK2 transcription factor related, locus 2
- NK2 transcription factor-like protein B
- Nkx2.2
- NKX2.2homeobox protein Nkx-2.2
- NKX2BNK-2 homolog B
|
![Western Blot NKX2.2 Antibody (883411) [Unconjugated]](http://images.novusbio.com/fullsize2/NKX2.2_MAB8167_Western_Blot_14480.jpg)
![Immunocytochemistry NKX2.2 Antibody (883411) [Unconjugated]](http://images.novusbio.com/fullsize2/NKX2.2_MAB8167_Immunocytochemistry_14546.jpg)
![Immunocytochemistry NKX2.2 Antibody (883411) [Unconjugated]](http://images.novusbio.com/fullsize2/NKX2.2_MAB8167_Immunocytochemistry_14547.jpg)
