Neuropilin-1 Products

Description

Neuropilin-1/CD304 is a type-I transmembrane protein. It forms a heterodimeric complex with vascular endothelial growth factor receptor 2, and this complex functions as a receptor for vascular endothelial growth factor. On the other hand, Neuropilin-1/CD304 forms a complex with plexin-1, and this complex acts as a semaphorin 3A receptor. Neuropilin-1/CD304 is involved in angiogenesis, axon guidance, cell survival, migration, and invasion. Recently, it has been reported that Neuropilin-1/CD304 is an essential component located on the immunological synapse and acts as a potent cell-surface marker for murine regulatory T cells (Treg). Neuropilin-1/CD304 expressed by Treg cells promotes long interactions between Treg cells and immature dendritic cells and restricts access of effector cells to the antigen-presenting cells.

Bioinformatics

Uniprot	AAH07533 Human AAH07533.1 Human NM_001024628 Human NM_001024629 Human NM_003873 Human NP_001019800 Human NP_001019800.1 Human NP_003864 Human O14786 Human
Product By Gene ID	8829
Alternate Names	BDCA4 CD304 antigen CD304 DKFZp686A03134 DKFZp781F1414 neuropilin 1 neuropilin-1 NP1 NRP transmembrane receptor Vascular endothelial cell growth factor 165 receptor VEGF165R

Research Areas for Neuropilin-1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Breast Cancer
Cancer
Phospho-Specific