Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Po, Bv
Applications: ELISA, IHC
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002).[supplied by OMIM]
Bioinformatics
Uniprot |
Human Human Human Human |
Product By Gene ID |
79661 |
Alternate Names |
- DNA-(apurinic or apyrimidinic site) lyase Neil1
- EC 3.2.2.-
- EC 4.2.99.18
- endonuclease 8-like 1
- endonuclease VIII
- Endonuclease VIII-like 1
- FLJ22402
- FPG1DNA glycosylase/AP lyase Neil1
- hFPG1
- NEH1
- nei endonuclease VIII-like 1 (E. coli)
- Nei homolog 1
- NEI1
- Nei-like protein 1
|
Research Areas for NEIL1
Find related products by research area and learn more about each of the different research areas below.
Base Excision RepairDNA Repair