Species: Hu, Mu, Rt
Applications: WB, IHC, KO
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Mitochondrial complex I (NADH-ubiquinone reductase; EC 1.6.5.3) is the first multimeric complex of the respiratory chain that catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mammalian mitochondrial complex I is an assembly of at least 43 different subunits. Seven of the subunits are encoded by the mitochondrial genome; the remainder are the products of nuclear genes. The iron-sulfur protein (IP) fraction of complex I is made up of 7 subunits, including NDUFS2. See NDUFS1 (MIM 157655).[supplied by OMIM]
Bioinformatics
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
4720 |
| Alternate Names |
- CI-49
- CI-49kD
- complex 1, mitochondrial respiratory chain, 49-KD subunit
- complex I 49kDa subunit
- Complex I-49kD
- EC 1.6.5.3
- EC 1.6.99.3
- EC 1.6.99.5
- NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49kD) (NADH-coenzyme Qreductase)
- NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Qreductase)
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
- NADH-ubiquinone oxidoreductase 49 kDa subunit
- NADH-ubiquinone oxidoreductase NDUFS2 subunit
|
