Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Chicken Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
Human PLP (also known as lipophilin) is a 30 kDa protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.
Bioinformatics
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
5354 |
| Alternate Names |
- HLD1
- Lipophilin
- lipophilin
- major myelin proteolipid protein
- MMPL
- myelin proteolipid protein
- PLP
- PLP/DM20
- PMD
- proteolipid protein 1
- spastic paraplegia 2, uncomplicated
- SPG2
|
