MEK2 Products

Description

MEK1 and MEK2 (MAPK kinase 1/2, or ERK kinase 1/2) are mitogen-activated protein kinases that stimulate MAP kinase activity, playing a role in both cell growth and differentiation (1,2). MEK itself is activated via phosphorylation at serines 217/218 and 221/222 by upstream activator kinases, including c-raf, mos and MEK kinase (3,4). MEK1 and MEK2 are activated by a wide variety of growth factors and cytokines, and also by membrane depolarization and calcium influx (5).

Bioinformatics

Entrez	5605 Human 58960 Rat
Uniprot	AAH00471 Human NM_030662 Human NP_109587 Human NP_109587.1 Human P36507 Human
Product By Gene ID	5605
Alternate Names	ERK activator kinase 2 MAPKK 2 MEK 2 MEK2EC 2.7.12.2 mitogen-activated protein kinase kinase 2 MKK2FLJ26075 p45 PRKMK2MAPKK2

Research Areas for MEK2

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Autophagy
Cancer
MAP Kinase Signaling
Phospho-Specific
Protein Kinase
Protein Phosphatase
Signal Transduction