Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
Description
Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus . Isoform 5 activates CDC42
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
23263 |
| Alternate Names |
- DBL's big sister
- DBS
- FLJ12122
- guanine nucleotide exchange factor DBS
- KIAA0362ARHGEF14
- MCF.2 cell line derived transforming sequence-like
- MCF2 transforming sequence-like protein
- MCF2-transforming sequence-like protein
- OST
|
Research Areas for MCF2L
Find related products by research area and learn more about each of the different research areas below.
Apoptosis
