MAT2A Products

Description

MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers, expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.

MAT1A and MAT2A antibodies are useful tools for cancer research and liver function research.

Bioinformatics

Entrez	171347 Rat 232087 Mouse 4144 Human
Uniprot	NM_005911 Human NP_005902 Human NP_005902.1 Human P31153 Human
Product By Gene ID	4144
Alternate Names	AdoMet synthase 2 AMS2 EC 2.5.1.6 MAT 2 MATA2SAMS2adoMet synthetase 2 MATII MAT-II Methionine adenosyltransferase 2 Methionine adenosyltransferase II methionine adenosyltransferase II, alpha S-adenosylmethionine synthase isoform type-2 S-adenosylmethionine synthetase isoform type-2

Research Areas for MAT2A

Find related products by research area and learn more about each of the different research areas below.

Amino Acids, Drugs and other small molecules
Cancer
Lipid and Metabolism
Signal Transduction

Related MAT2A Blog Posts

Check out the latest blog posts on MAT2A.

MAT2a, MAT2b, HIF-1 alpha: Roles in Liver Cancer and DNA methylation Methionine Adenosyltransferase II alpha, also known as MAT2a, is a catalytic subunit of methionine adenosyltransferase (MAT) and essential enzyme for the catalysis of the principle biological methyl donor, S-adenosylmethionine (SAM) from methionine an...    Read more.

MAT2A - A Protien Coding Gene The enzyme S-adenosylmethionine synthetase, or MAT, catalyzes the formation of S- adenosylmethionine (AdoMet or SAMe) from methionine and ATP. AdoMet is the principal biological source of synthesized methyl, and is found in all cells but most prominen...    Read more.

Read more MAT2A related blogs.