MAP4K2 Products

Description

MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. MAP4K2 can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Bioinformatics

Entrez	5871 Human
Uniprot	M4K2_HUMAN Human NP_004570 Human NP_004570.2 Human Q12851 Human
Product By Gene ID	5871
Alternate Names	B lymphocyte serine/threonine protein kinase B lymphocyte serine/threonine-protein kinase BL44 EC 2.7.11 EC 2.7.11.1 GC kinase GCKMEK kinase kinase 2 Germinal center kinase germinal centre kinase (GC kinase) MAPK/ERK kinase kinase kinase 2 mitogen-activated protein kinase kinase kinase kinase 2 Rab8 interacting protein Rab8-interacting protein RAB8IPMEKKK 2

Research Areas for MAP4K2

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Signal Transduction