LOX propeptide Products

Description

Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. LOX plays a vital role in the formation and repair of the extracellular matrix. In addition, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, Lysyl oxidase is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.

Bioinformatics

Entrez	16948 Mouse 4015 Human
Uniprot	P28300 Human P28301 Mouse
Product By Gene ID	4015
Alternate Names	lysyl oxidaseEC 1.4.3.13 MGC105112 protein-lysine 6-oxidase

Research Areas for LOX propeptide

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cytoskeleton Markers
Endothelial Cell Markers
Extracellular Matrix
Hypoxia
Signal Transduction

Related LOX propeptide Blog Posts

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LOX propeptide: A novel peptide cancer therapeutic Lysyl oxidase, also known as LOX, is a copper-dependent enzyme that cross-links collagen and elastin through the oxidative deamination of peptidyl lysine (collagen and elastin) and hydroxylysine (collagen only) residues, thereby playing a critical rol...    Read more.

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