IL-9R Products

Description

The protein encoded by the IL9R gene is a cytokine receptor that specifically mediates the biological effects ofinterleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor,gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of thisreceptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologicresponses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested anassociation of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 havebeen described. Alternatively spliced transcript variants have been found for this gene. (provided by RefSeq)

Bioinformatics

Entrez	3581 Human
Uniprot	AAH51337 Human NM_176786 Human Q01113 Human
Product By Gene ID	3581
Alternate Names	CD129 antigen CD129 IL-9 receptor IL-9R interleukin 9 receptor interleukin-9 receptor