Species: Hu
Applications: WB, B/N, CyTOF-ready, Flow
Host: Goat Polyclonal
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Species: Mu
Applications: WB, ICC/IF
Host: Rat Monoclonal
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Description
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
11009 |
| Alternate Names |
- C49A
- FISP
- IL10B
- IL-24
- interleukin 24
- mda-7
- MDA-7
- MDA7MOB5
- melanocyte-associated Mda-7
- melanoma differentiation association protein 7
- Melanoma differentiation-associated gene 7 protein
- Mob-5
- ST16interleukin-24
- suppression of tumorigenicity 16 (melanoma differentiation)
- Suppression of tumorigenicity 16 protein
|
Research Areas for IL-24
Find related products by research area and learn more about each of the different research areas below.
ApoptosisCancer
![Neutralization IL-24 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/IL-24_AF1965_Block_Neutralize_8808.jpg)
![N/A IL-24 [Biotin]](http://images.novusbio.com/fullsize2/DATA_IL24_DY1965_ELISA_1739.jpg)
![N/A IL-24 [Biotin]](http://images.novusbio.com/fullsize2/DATA_IL24_DY278605_ELISA_2406.jpg)
