Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Binding Activity
Species: Hu
Applications: AC
Description
Official Gene Symbol: IL20RA Gene ID: 53832 (Human) Gene Map Locus: 6q22.33-q23.1 (Human) IL20RA, is a subunit of IL20R, a member of Cytokine Class II receptor super family. It consists of a central transmembrane domain and functionally induces IL20 and IL26 signaling in epithelial cells and keratinocytes. It associates with IL-20RB and forms a functional receptor complex for IL20, IL19, and IL24. It also associates with IL-10RB and forms a unique heterodimeric functional receptor complex for IL-26. Upon ligand binding, it induces signaling through activation of STAT3 and STAT1. IL20RA is specifically expressed in skin suggesting a prominent role in growth and proliferation of keratinocytes.
Bioinformatics
Entrez |
Mouse Human Mouse |
Uniprot |
Human Human |
Product By Gene ID |
53832 |
Alternate Names |
- class II cytokine receptor ZCYTOR7
- CRF2-8
- Cytokine receptor class-II member 8
- Cytokine receptor family 2 member 8
- FLJ40993
- IL-20R1IL-20 receptor subunit alpha
- IL-20RA
- IL-20R-alpha
- interleukin 20 receptor, alpha
- interleukin-20 receptor I
- interleukin-20 receptor subunit alpha
- ZCYTOR7
- ZcytoR7
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