HSPH1/HSP105 Products

Description

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins and the HSP 110 family. The HSP 110 family (also known as the HSP 105 family) is composed of HSP 105, Apg-1 and Apg-2. HSP 105 is a testis-specific and HSP 90-related protein. Research indicates that HSP 105 is specifically localized in the germ cells and may translocate into the nucleus after heat shock. It is suggested that HSP 105 may contribute to the stabilization of p53 proteins in the cytoplasm of the germ cells, preventing the potential induction of apoptosis by p53.

Bioinformatics

Entrez	10808 Human 15505 Mouse 288444 Rat
Uniprot	NM_006644 Human NP_006635 Human NP_006635.2 Human Q92598 Human
Product By Gene ID	10808
Alternate Names	Antigen NY-CO-25 heat shock 105kD beta heat shock 105kDa protein 1 heat shock 105kDa/110kDa protein 1 Heat shock 110 kDa protein heat shock protein 105 kDa HSP105A HSP105B HSP105heat shock 105kD alpha HSP110 KIAA0201DKFZp686M05240 NY-CO-25