Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, IP
Host: Mouse Monoclonal
Species: Hu, Rt
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Description
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
11036 |
Alternate Names |
- 1-like factor
- general transcription factor IIA, 1-like
- GTF2A1LF
- MGC26254
- TFIIA large subunit isoform ALF
- TFIIA-alpha and beta-like factor
- TFIIA-alpha/beta-like factor
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