Cytokeratin 7/13/17/18 Products

Description

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. Keratin 17 is expressed in suprabasal keratinocytes of wounded epidermis. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. LdS 23 is useful for studies of epithelial cells and tumour origin.

Bioinformatics

Product By Gene ID	3855
Alternate Names	CK7 CK-7 cytokeratin 7 Cytokeratin-7 cytokeratin-7 K2C7 K7keratin, 55K type II cytoskeletal keratin 7 keratin, type II cytoskeletal 7 Keratin-7 keratin-7 MGC129731 MGC3625 Sarcolectin sarcolectin SCLkeratin, simple epithelial type I, K7 type II mesothelial keratin K7 Type-II keratin Kb7

Research Areas for Cytokeratin 7/13/17/18

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Cytoskeleton Markers