Collagen II Products

Description

The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

Bioinformatics

Entrez	1280 Human 12824 Mouse 25412 Rat 395069 Chicken 407142 Bovine
Uniprot	AAH07252 Human NP_001835 Human P02458 Human Q90W37 Chicken
Product By Gene ID	1280
Alternate Names	Alpha-1 type II collagen ANFH AOM cartilage collagen chondrocalcin COL11A3 Collagen 2 collagen alpha-1(II) chain collagen II, alpha-1 polypeptide collagen type 2 collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphysealdysplasia, congenital) collagen, type II, alpha 1 Collagen-2 MGC131516 SEDC

Research Areas for Collagen II

Find related products by research area and learn more about each of the different research areas below.

Cytoskeleton Markers
Extracellular Matrix
Stem Cell Markers