Species: Hu, Mu
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA, ICC/IF, IHC, ICC/IF
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
CEP290 encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
80184 |
| Alternate Names |
- BBS14Bardet-Biedl syndrome 14 protein
- Cancer/testis antigen 87
- centrosomal protein 290kDa
- Cep290
- CT87JBTS6
- FLJ13615
- JBTS5CTCL tumor antigen se2-2
- KIAA0373FLJ21979
- LCA10monoclonal 3H11 antigen
- MKS4
- Nephrocystin-6
- NPHP6centrosomal protein of 290 kDa
- POC3 centriolar protein homolog
- POC3
- prostate cancer antigen T21
- rd16,3H11AG
- SLSN6nephrocytsin-6,3H11Ag
- Tumor antigen se2-2
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Research Areas for CEP290
Find related products by research area and learn more about each of the different research areas below.
Vision
Related CEP290 Blog Posts
Check out the latest blog posts on CEP290.
LAMP2: Protector of the lysosome
LAMP2 belongs to the family of membrane glycoproteins who confer selectins with carbohydrate ligands. LAMP2 has been implicated in tumor cell metastasis, as well as overall protection, maintenance, and adhesion of the lysosome. It appears that LAMP2 m... Read more.
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