CD79A Products

Description

CD79a is a disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines.

Bioinformatics

Entrez	12518 Mouse 681236 Rat 973 Human
Uniprot	NM_001783 Human NP_001774 Human NP_001774.1 Human P11912 Human
Product By Gene ID	973
Alternate Names	CD79A antigen (immunoglobulin-associated alpha) CD79a antigen CD79a molecule, immunoglobulin-associated alpha IGAB-cell antigen receptor complex-associated protein alpha chain ig-alpha Ig-alpha MB-1 membrane glycoprotein MB1 MB-1 Membrane-bound immunoglobulin-associated protein Surface IgM-associated protein

Research Areas for CD79A

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Adaptive Immunity
Cell Biology
Immunology
Phospho-Specific

Related CD79A Blog Posts

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CD79b - A Signal Transduction Component of the B-cell Receptor The B-cell antigen receptor (BCR) is a complex multimeric aggregate that includes the following key noncovalently-bound components: antigen-specific surface immunoglobulin (Ig), CD79a (Ig-alpha), and CD79b (Ig-beta). BCR signaling is a pivotal pathway...    Read more.

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