CARS Products

Description

CARS encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Bioinformatics

Entrez	833 Human
Uniprot	AAH02880 Human NP_001014437 Human NP_001742 Human NP_001742.1 Human NP_644802 Human Q5HYE4 Human
Product By Gene ID	833
Alternate Names	CARS1 CYSRS CysRS cysteine translase cysteine tRNA ligase 1, cytoplasmic Cysteine--tRNA ligase cysteinyl-tRNA synthetase cysteinyl-tRNA synthetase, cytoplasmic EC 6.1.1 EC 6.1.1.16 MGC:11246