CARS Antibody

CARS encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using NBP1-86624	Applications	Species
Han-Kui Liu, Hong-Lin Hao, Hui You, Feng Feng, Xiu-Hong Qi, Xiao-Yan Huang, Bo Hou, Chang-Geng Tian, Han Wang, Huan-Ming Yang, Jian Wang, Rui Wu, Hui Fang, Jiang-Ning Zhou, Jian-Guo Zhang, Zhen-Xin Zhang A Cysteinyl-tRNA Synthetase Mutation Causes Novel Autosomal-Dominant Inheritance of a Parkinsonism/Spinocerebellar-Ataxia Complex. Neuroscience bulletin 2024-06-13 [PMID: 38869703]
Xiu-Hong Qi, Peng Chen, Yue-Ju Wang, Zhe-Ping Zhou, Xue-Chun Liu, Hui Fang, Chen-Wei Wang, Ji Liu, Rong-Yu Liu, Han-Kui Liu, Zhen-Xin Zhang, Jiang-Ning Zhou Increased cysteinyl-tRNA synthetase drives neuroinflammation in Alzheimer’s disease Translational Neurodegeneration 2024-01-08 [PMID: 38191451]
Stadler C, Hjelmare M, Neumann B et al. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. J Proteomics 2012-04-03 [PMID: 22361696]

Array NBP1-86624

• CARS Antibodies
• CARS Lysates
• CARS Proteins