CARD11/CARMA1 Products

Description

CARD11 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Bioinformatics

Entrez	108723 Mouse 84433 Human
Uniprot	NM_032415 Human NP_115791 Human NP_115791. Human Q9BXL7 Human
Product By Gene ID	84433
Alternate Names	BIMP3card-maguk protein 1 CARD-containing MAGUK protein 1 Carma 1 CARMA1bcl10-interacting maguk protein 3 caspase recruitment domain family, member 11 caspase recruitment domain-containing protein 11 MGC133069

Research Areas for CARD11/CARMA1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis