BAIAP2 Products

Description

BAIAP2 is encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Alternative splicing of the 3'-end of this gene results in three products of undetermined function.

Bioinformatics

Entrez	10458 Human
Uniprot	AAH32559 Human NM_006340 Human NM_017450 Human NP_006331 Human NP_006331. Human NP_006331.1 Human NP_059344.1 Human NP_059345 Human NP_059345.1 Human Q9UQB8 Human
Product By Gene ID	10458
Alternate Names	BAI1-associated protein 2IRS-58 BAI-associated protein 2 BAP2 brain-specific angiogenesis inhibitor 1-associated protein 2 Fas ligand-associated factor 3 FLAF3 Insulin receptor substrate p53 Insulin receptor substrate p53/p58 Insulin receptor substrate protein of 53 kDa IRSp53 IRSP53 IRSp53/58 Protein BAP2

Research Areas for BAIAP2

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Signal Transduction