ALDH1A2 Products

Description

ALDH1A2 belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Bioinformatics

Entrez	8854 Human
Uniprot	NM_170696 Human NP_733797.1 Human NP_733798 Human O94788 Human
Product By Gene ID	8854
Alternate Names	aldehyde dehydrogenase 1 family, member A2 Aldehyde dehydrogenase family 1 member A2 EC 1.2.1 EC 1.2.1.36 RALDH 2 RALDH(II) RalDH2 RALDH2MGC26444 RALDH2-T retinal dehydrogenase 2 Retinaldehyde-specific dehydrogenase type 2