Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Dr, Bv
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC)transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes aredivided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of theMDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigenpresentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to thecytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis.Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia. (provided by RefSeq)
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
22 |
| Alternate Names |
- ABC transporter 7 protein
- ABC7ATP-binding cassette sub-family B member 7, mitochondrial
- ASATATP-binding cassette 7
- Atm1p
- ATP-binding cassette transporter 7
- ATP-binding cassette, sub-family B (MDR/TAP), member 7
- EC 3.6.3
- EC 3.6.3.42
- EST140535
|
