Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
AAK1 (AP2-associated kinase 1) is a Ser/Thr protein kinase. The rat homolog was first identified in a screen of a rat brain cDNA library using a domain of the alpha subunit of the heterotetrameric AP2 complex as bait. The AP2 complex is one of two major coat proteins of endocytic vesicles that function in receptor-mediated endocytosis and the recycling of synaptic vesicles. AAK1 is responsible for phosphorylating the mu subunit of AP2 to promote clathrin-mediated endocytosis.
Bioinformatics
Entrez |
Human Mouse Rat |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
22848 |
Alternate Names |
- Adaptor-associated kinase 1
- AP2 associated kinase 1
- AP2-associated protein kinase 1
- DKFZp686F03202
- DKFZp686K16132
- EC 2.7.11.1
- FLJ23712
- FLJ25931
- FLJ31060
- FLJ45252
- KIAA1048FLJ42882
- MGC138170
- MGC164568
- MGC164570
|
Research Areas for AAK1
Find related products by research area and learn more about each of the different research areas below.
Protein Kinase