58K Golgi Protein Products

Description

58K protein antibodies are excellent for use as markers for the Golgi complex. The 58K protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency; also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.

Bioinformatics

Entrez	10841 Human 14317 Mouse 89833 Rat
Uniprot	AAD13030 Human NP_006648 Human NP_006648 Human NP_006648.1 Human NP_996848 Human NP_996848 Human NP_996848.1 Human O88618 Rat O95954 Human Q91XD4 Mouse
Product By Gene ID	10841
Alternate Names	formimidoyltransferase cyclodeaminase formimidoyltransferase-cyclodeaminase formiminotransferase cyclodeaminase Formiminotransferase-cyclodeaminase human formiminotransferase cyclodeaminase, EC 4.3.1.410formiminotransferase-cyclodeaminase LCHC1

Research Areas for 58K Golgi Protein

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Golgi Apparatus Markers
Lipid and Metabolism
Phospho-Specific
Signal Transduction