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Animal Models to Study Autophagy

Autophagy Signaling Pathway, Novus Biologicals, macroautophagy induction, elongation, microautophagy, autophagosome maturation, autolysosome

By Christina Towers, PhD

Tags: 
ULK1
ATG13
rb1cc11
beclin-1
AMBRA1
ATG14
vps14/pik3r4
VPS34
ATG9A
ATG7
Atg10
ATG12
ATG5
ATG4B
Atg3
LC3B
p62-sqstm1
Autophagy
autophagosome
Christina Towers
mCherry
GFP
Zebrafish
Animal models

Best Methods to Induce and Inhibit Autophagy Pharmacologically

VPS35 expression in endosomes and lysosomes of human U-2 OS cells, ICC

By Christina Towers, PhD

Tags: 
Autophagy
autophagosome
LC3
LC3B
Bafilomycin
Chloroquine
Lysosome
Western blot
Beclin 1
VPS34
ULK1
ATG4B
mTOR
autophagy induction
autophagy inhibition
Christina Towers
Cancer
rapamycin
Autophagic flux

mTOR Signaling and the Tumor Microenvironment

mTOR signaling pathway poster

By Yoskaly Lazo-Fernandez, PhD

Tags: 
TOR/mTOR
mTORC1
mTORC2
mTOR
TME
PI3K
HIF-1 alpha
S6K1
Akt
PKC
SGK3
FoxO1/3
CD4
CD8
HIF-1
VEGF
HIF-1 beta

Negative feedback regulation of EPAS1 gene in non-small cell lung cancer through DNA methyltransferases

HIF-1 alpha expression in human lung tissue, IHC

By Jamshed Arslan Pharm.D.

Tags: 
Cancer
Epigenetics
Hypoxia
HIF-1 alpha
HIF-2 alpha
HIF-1 beta
EPAS1
ChIP
DNMT1
DNMT3a
Dnmt3b
Non-Small Cell Lung Cancer

Nickel induces migratory and invasive phenotype in human epithelial cells by epigenetically activating ZEB1

Epigenetic mechanisms Novus Biologicals

By Jamshed Arslan Pharm.D.

Tags: 
Cancer
Cancer Research
Epigenetics
Histones
ZEB1
EMT
Cadherin
claudin-1
Fibronectin
histone-h3
ChIP

A link between Autophagy and Apoptosis: Chat with First Author Brent E. Fitzwalter

Apoptosis poster Novus Biologicals

By Christina Towers, PhD.

Tags: 
Autophagy
autophagosome
Lysosome
Apoptosis
FOXO3A
PUMA

Bad news for stomach cancer: BAMBI protein inhibits gastric carcinoma via TGF-beta/epithelial-mesenchymal transition signaling

Collagen-I expression in rat colon tissue IHC

By Jamshed Arslan Pharm.D.

Tags: 
Epigenetics
Cancer
Tumor
Hypoxia
TGF-beta
HIF-1 alpha
Bambi
SOX4
VIM
MMP9
Ki67
IPO-38
N-cadherin
Collagen-1
Snai1
Acta2
Twist1
Fibronectin
EMT

Chemotherapy-induced metastasis: An unexpected foe?

Mena plasma membrane, cytosol and focal adhesion expression in human cell line U-2 OS ICC

By Yoskaly Lazo-Fernandez, PhD

Tags: 
TMEM
Breast Cancer
Tie-2
VEGF
ATF3
MENA
macrophages
Metastasis
T Cells
NK cells
immunology
Cancer
Cancer Research

Advancing CAR T Therapies with CRISPR/Cas9

Expression of CD4 and CD8 in peripheral blood mononuclear cells ICC

By Victoria Osinski

Tags: 
CRISPR-Cas9
Lymphocytes
T Cells
Tumor
Cancer
Cancer Research
CAR-T
Immunotherapy
Immuno-oncology
immunology
CRISPR/Cas9

Combined NOTCH/MAPK inhibition: A promising new anticancer approach

MAPK signaling pathway Novus Biologicals

By Yoskaly Lazo-Fernandez, PhD

Tags: 
NOTCH
MAPK
Colon Cancer
MEK
EMT
NICD
FRA1
Cancer
Metastasis
Tumor

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