Novus Biologicals products are now on bio-techne.com

Caspase-9 Products

Antibodies
ELISA Kits
Mouse Caspase-9 ELISA Kit (Co ...
Mouse Caspase-9 ELISA Kit (Colorim...
NBP2-75042
Species: Mu
Applications: ELISA
Rat Caspase-9 ELISA Kit (Colo ...
Rat Caspase-9 ELISA Kit (Colorimet...
NBP2-75044
Species: Rt
Applications: ELISA
Human Caspase-9 ELISA Kit (Co ...
Human Caspase-9 ELISA Kit (Colorim...
NBP1-83734
Species: Hu
Applications: ELISA
Lysates
Caspase-9 Overexpression Lysa ...
Caspase-9 Overexpression Lysate
NBP2-05935
Species: Hu
Applications: WB
Proteins
Caspase-9 Antibody Blocking P ...
Caspase-9 Antibody Blocking Peptide
NB100-56121PEP
Species: Hu
Applications: AC
Caspase-9 Antibody Blocking P ...
Caspase-9 Antibody Blocking Peptide
NBP1-76961PEP
Species: Hu
Applications: AC
Caspase-9 Recombinant Protein ...
Caspase-9 Recombinant Protein Antigen
NBP2-47557PEP
Species: Hu
Applications: AC

Description

Caspase 9 (CASP9) is a member of the cysteine-aspartic acid protease (caspase) family that is involved in the execution-phase of cell apoptosis. Caspase 9 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 9 form.

There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Caspase 3 is considered an initiator, as initiated caspase-9 goes on to cleave the effector procaspase-3 and procaspase-7.

Caspase 9 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.

Bioinformatics

Entrez Mouse
Rat
Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 842
Alternate Names
  • APAF-3APAF3
  • apoptotic protease activating factor 3
  • Apoptotic protease Mch-6
  • Apoptotic protease-activating factor 3
  • CASP-9
  • caspase 9, apoptosis-related cysteine peptidase
  • caspase-9
  • EC 3.4.22.62
  • ICE-LAP6CASPASE-9c
  • ICE-like apoptotic protease 6
  • MCH6apoptosis-related cysteine protease

Research Areas for Caspase-9

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Caspases
Cell Biology
Phospho-Specific

Related Caspase-9 Blog Posts

Check out the latest blog posts on Caspase-9.
A New Standard in Antibody Testing - Simple Western Certified Antibodies
The Western blot is one of the most commonly used antibody assay techniques in cell and molecular biology research since its development over three decades ago, and is considered the gold standard for protein detection and quantification. The tradi...    Read more.
The Ins and Outs of Survivin
By Rachel M.A. Linger, Ph.D.What is survivin?Survivin is a small (16.5 kDa) protein normally found in human fetal tissue. In contrast, survivin is typically undetectable in most normal adult tissues. Expression of ...    Read more.
Pyroptosis: Mechanisms mediating cell death and pro-inflammatory cytokine release
By Victoria OsinskiPyroptosis is an inflammatory form of programmed cell death characterized by the release of pro-inflammatory cytokines IL-1 beta and IL-18.1,10 It is a process distinct from apoptosis and necrosis (T...    Read more.
Caspase 9 - an important apoptosis marker
Caspases are essential mediators of programmed cell death and are needed for both the induction of apoptosis as well as for aiding the degradation of cellular structures. Initiator caspases (such as Caspase-9) sense and respond to various signals i...    Read more.
Caspase-3, The Executioner of Apoptosis
The Role of Caspase-3 in ApoptosisCaspase-3 enzyme is a member of the family of endoproteases which regulate inflammation and apoptosis signaling networks. Caspase-3 is known as an executioner caspase in apoptosis because of its role in coordinat...    Read more.
Read more Caspase-9 related blogs.