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Synapsin I

Synapsin I, a pre-synaptic marker

Synapsin-I, also called Synapsin 1/Syn1, is an ~80 kDa protein (predicted mol. wt. 74.1 kDa) which belongs to the Synapsin family (Synapsin I, Synapsin II, Synapsin III). Synapsins are the evolutionarily conserved phospho-proteins which are associated with the cytosolic side of the synaptic vesicles. They tether the vesicles to the actin cytoskeleton, thus forming a reserve pool.