Novus Biologicals products are now on bio-techne.com

Enolase 2

Epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinoma (HNSCC)

Head and neck squamous cell carcinoma is quite common in the U.S., covering more than 4% of all cancers each year, and is most susceptible to individuals between 50 and 60 years of age.  Squamous cells are a type of epithelial cell that are located all over the body with concentrations in the mouth, throat, neck and cervix.  EGFR, or epidermal growth factor receptor, is a trans-membrane glycoprotein that oversees cellular proliferation through its intrinsic tyrosine kinase activity.  When EGFR is bound to its ligand, it is phosphorylated by inner tyrosine kinase activity, where down