Novus Biologicals products are now on bio-techne.com

caspase-10 antibodies

Caspase 10 - an initiator caspase in the extrinsic death receptor pathway

Apoptosis, also called programmed cell death, is an essential process in development and disease. The signaling networks that carry out apoptosis is consists of a series of endoproteases called caspases which are synthesized as inactive zymogens. Caspses are grouped into two classes: initiator caspases and effector caspases. Initiator caspases are activated by the assembly of multi-protein complexes such as the death-inducing signaling complex (DISC) (1).