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AADC

How DOPA Decarboxylase Affects Neurotransmitter Synthesis

DOPA decarboxylase (DDC) is responsible for catalyzing the conversion of aromatic amino acids into their corresponding amines during the synthesis of several important neurotransmitters. Specifically, DDC catalyzes the decarboxylation of L-DOPA to dopamine, L5-HTP to serotonin, L-histidine to histamine, phenylalanine to phenethylamine, L-tyrosine to tyramine, and tryptophan to tryptamine.