Steroid receptors (SRs) are a superfamily of ligand-dependent nuclear transcription factors that activate responsive genes response to hormone. Androgen receptors (ARs) are found in a wide variety of tissues, including reproductive organs, central nervous system (CNS), and skeletal muscle. AR signaling is fundamental for the development and function of male reproductive organs, but also plays a role in non-reproductive organs such as muscle, hair follicles, and brain.
