WNK4 Products

Description

WNK lysine deficient protein kinase 4 (WNK4) is a cytoplasmic serine-threonine kinase expressed in the distal nephron which likely plays an important role in hypertension. The role of WNK4 in kidney physiology is to act as a molecular switch between NaCl reabsorption (volume retention) and K+ secretion (waste release).

WNK4 mutations have been associated with an autosomal dominant disease called pseudohypoaldosteronism type II.

Bioinformatics

Entrez	65266 Human
Uniprot	NP_115763 Human NP_115763.2 Human Q96J92 Human
Product By Gene ID	65266
Alternate Names	EC 2.7.11 EC 2.7.11.1 PHA2B PRKWNK4protein kinase, lysine deficient 4 Protein kinase lysine-deficient 4 Protein kinase with no lysine 4 serine/threonine-protein kinase WNK4 WNK lysine deficient protein kinase 4

Research Areas for WNK4

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Potassium Channels
Protein Kinase
Signal Transduction