SP1 Products

Description

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling

Bioinformatics

Entrez	20683 Mouse 24790 Rat 6667 Human
Uniprot	NP_612482 Human NP_612482.2 Human NP_612482.2. Human P08047 Human
Product By Gene ID	6667
Alternate Names	Sp1 transcription factor specificity protein 1 transcription factor Sp1 TSFP1

Research Areas for SP1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Phospho-Specific
Transcription Factors and Regulators

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