TSH beta Antibody (Fc1005) Summary
Immunogen |
Human Thyroid Stimulating Hormone |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
TSHB |
Purity |
Ion exchange chromatography |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:100 - 1:2000
- Immunoprecipitation 1:10 - 1:500
- Radioimmunoassay 1:100 - 1:2000
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
0.01M potassium phosphate, 0.135M NaCl, 1 mg/ml BSA, and 2.5mMKCl |
Preservative |
0.05% Sodium Azide |
Purity |
Ion exchange chromatography |
Alternate Names for TSH beta Antibody (Fc1005)
Background
Thyroid-stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle-stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Thyroid Stimulating Hormone Antibody (NBP1-78579) (0)
Secondary Antibodies
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