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Oval Cell Marker Antibody (OC2-6E10) [Janelia Fluor® 635]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, IHC
Clone
OC2-6E10
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 635

Order Details

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Oval Cell Marker Antibody (OC2-6E10) [Janelia Fluor® 635] Summary

Immunogen
Nonparenchymal cells from DDC-treated mice to induce the oval cell response.
Localization
Cell surface
Marker
Hepatic periductal cell Marker
Specificity
Specific for proliferating hepatic periductal cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Purity
Tissue culture supernatant
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Tissue culture supernatant

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Background

Facultative liver stem cell activation was originally described in the rat, where chemical damage and partial hepatectomy caused the emergence of a new cell type, the oval cell. These cells are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts (1). To properly determine the molecular regulation of the progenitor process, appropriate markers are needed to identify and isolate cells that emerge during the oval cell response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Additional Oval Cell Marker Products

Array NBP1-18981JF635

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