Mouse IGFBP-2 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

We have publications tested in 2 confirmed species: Mouse, Transgenic Mouse.

Showing Publications 1 - 3 of 3.

Publications using DY797	Applications	Species
P Fahlbusch, B Knebel, T Hörbelt, DM Barbosa, A Nikolic, S Jacob, H Al-Hasani, F Van de Vel, Y Van Nieuwe, D Müller-Wie, B Lapauw, DM Ouwens, J Kotzka Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men Int J Mol Sci, 2020-06-10;21(11):. 2020-06-10 [PMID: 32532003] (Mouse, Transgenic Mouse)		Mouse, Transgenic Mouse
Zhao X, Ze Y, Gao G, Sang X, Li B, Gui S, Sheng L, Sun Q, Cheng J, Cheng Z, Hu R, Wang L, Hong F Nanosized TiO2-induced reproductive system dysfunction and its mechanism in female mice. PLoS ONE, 2013-04-02;8(4):e59378. 2013-04-02 [PMID: 23565150] (Mouse)		Mouse
Wahl EC, Aronson J, Liu L, Fowlkes JL, Thrailkill KM, Bunn RC, Skinner RA, Miller MJ, Cockrell GE, Clark LM, Ou Y, Isales CM, Badger TM, Ronis MJ, Sims J, Lumpkin CK Restoration of regenerative osteoblastogenesis in aged mice: modulation of TNF. J. Bone Miner. Res., 2010-01-01;25(1):114-23. 2010-01-01 [PMID: 19580462] (Mouse)		Mouse

Array DY797

• IGFBP-2 Antibodies
• IGFBP-2 ELISA Kits
• IGFBP-2 Protein
• IGFBP-2 ELISAs
• IGFBP-2 Proteins and Enzymes