Rat IgG2b Isotype Control (141945) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Porcine.

We have publications tested in 14 applications: Bioassay, Control, Flow Cytometry, Flow Cytometry Control, Functional Assay, ICC, IHC, IHC-Fr, IHC-P, In Vivo, In vivo assay, Isotype Control, Neutralization, Neutralization Control.

Showing Publications 1 - 10 of 56. Show All 56 Publications. Collapse Publications.

Publications using MAB0061	Applications	Species
Ye, S;Agalave, NM;Ma, F;Mahmood, DFD;Al-Grety, A;Khoonsari, PE;Leng, L;Svensson, CI;Bucala, R;Kultima, K;Vera, PL; MIF-Modulated Spinal Proteins Associated with Persistent Bladder Pain: A Proteomics Study International journal of molecular sciences 2024-04-19 [PMID: 38674069] (In vivo assay, Mouse)	In vivo assay	Mouse
Chen, C;Lin, LY;Chen, JW;Chang, TT; CXCL5 suppression recovers neovascularization and accelerates wound healing in diabetes mellitus Cardiovascular diabetology 2023-07-07 [PMID: 37420254] (Neutralization Control, Mouse)	Neutralization Control	Mouse
T Ono, T Yamashita, R Kano, M Inoue, S Okada, K Kano, S Koizumi, K Iwabuchi, Y Hirabayash, I Matsuo, Y Nakashima, H Kamiguchi, Y Kohro, M Tsuda GPR55 contributes to neutrophil recruitment and mechanical pain induction after spinal cord compression in mice Brain, Behavior, and Immunity, 2023-03-08;110(0):276-287. 2023-03-08 [PMID: 36898418] (Neutralization, Mouse)	Neutralization	Mouse
T Ono, T Yamashita, R Kano, M Inoue, S Okada, K Kano, S Koizumi, K Iwabuchi, Y Hirabayash, I Matsuo, Y Nakashima, H Kamiguchi, Y Kohro, M Tsuda GPR55 contributes to neutrophil recruitment and mechanical pain induction after spinal cord compression in mice Brain, Behavior, and Immunity, 2023;110(0):276-287. 2023 [PMID: 36898418] (Neutralization, Mouse)	Neutralization	Mouse
A Jarade, Z Garcia, S Marie, A Demera, I Prinz, P Bousso, JP Di Santo, N Serafini Inflammation triggers ILC3 patrolling of the intestinal barrier Nature Immunology, 2022-08-23;0(0):. 2022-08-23 [PMID: 35999393] (In Vivo, Mouse)	In Vivo	Mouse
W Dai, M Yang, P Xia, C Xiao, S Huang, Z Zhang, X Cheng, W Li, J Jin, J Zhang, B Wu, Y Zhang, PH Wu, Y Lin, W Wu, H Zhao, Y Zhang, WJ Lin, X Ye A functional role of meningeal lymphatics in sex difference of stress susceptibility in mice Nature Communications, 2022-08-16;13(1):4825. 2022-08-16 [PMID: 35974004] (In Vivo, Mouse)	In Vivo	Mouse
Y Huang, E Motta, C Nanvuma, LD Kuhrt, Y Yuan, P Xia, M Lubas, S Zhu, M Schnauss, N Qazi, F Hu, H Zhang, T Lei, M Synowitz, C Flüh, H Kettenmann Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model Cell Reports, 2022-04-12;39(2):110670. 2022-04-12 [PMID: 35417708] (Neutralization Control, Mouse)	Neutralization Control	Mouse
MJ Tosiek, K Groesser, A Pekcec, M Zwirek, G Murugesan, E Borges Activation of the Innate Immune Checkpoint CLEC5A on Myeloid Cells in the Absence of Danger Signals Modulates Macrophages' Function but Does Not Trigger the Adaptive T Cell Immune Response Journal of Immunology Research, 2022-02-25;2022(0):9926305. 2022-02-25 [PMID: 35252461] (Control, Human)	Control	Human
JR Dayton, Y Yuan, LP Pacumio, BG Dorflinger, SC Yoo, MJ Olson, SI Hernández-, MM McMahon, L Cruz-Oreng Expression of IL-20 Receptor Subunit beta Is Linked to EAE Neuropathology and CNS Neuroinflammation Frontiers in Cellular Neuroscience, 2021-09-07;15(0):683687. 2021-09-07 [PMID: 34557075] (In Vivo, Mouse)	In Vivo	Mouse
K Cosker, A Mallach, J Limaye, TM Piers, J Staddon, SJ Neame, J Hardy, JM Pocock Microglial? signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome Scientific Reports, 2021-06-25;11(1):13316. 2021-06-25 [PMID: 34172778] (Functional Assay, Human)	Functional Assay	Human
L Andreasson, H Evenbratt, R Mobini, S Simonsson Differentiation of induced pluripotent stem cells into definitive endoderm on Activin A-functionalized gradient surfaces J Biotechnol, 2020-11-02;0(0):. 2020-11-02 [PMID: 33147515] (ICC, Human)	ICC	Human
RJ Napier, EJ Lee, MP Davey, EE Vance, JM Furtado, PE Snow, KA Samson, SJ Lashley, BR Brown, R Horai, MJ Mattapalli, B Xu, MC Callegan, LS Uebelhoer, CL Lancioni, RK Vehe, BA Binstadt, JR Smith, RR Caspi, HL Rosenzweig T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis Nat Commun, 2020-10-26;11(1):5406. 2020-10-26 [PMID: 33106495] (Functional Assay, Mouse)	Functional Assay	Mouse
Y Gong, T Suzuki, H Kozono, M Kubo, N Nakano Tumor-infiltrating CD62L+PD-1-CD8 T cells retain proliferative potential via Bcl6 expression and replenish effector T cells within the tumor PLoS ONE, 2020-08-26;15(8):e0237646. 2020-08-26 [PMID: 32845913] (Isotype Control, Mouse)	Isotype Control	Mouse
D Andreev, M Liu, D Weidner, K Kachler, M Faas, A Grüneboom, U Schlötzer-, LE Muñoz, U Steffen, B Grötsch, B Killy, G Krönke, AM Luebke, A Niemeier, F Wehrhan, R Lang, G Schett, A Bozec Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin J. Clin. Invest., 2020-09-01;0(0):. 2020-09-01 [PMID: 32773408] (Bioassay, Neutralization, Mouse)	Bioassay, Neutralization	Mouse
Jenny Bottek, Camille Soun, Julia K. Lill, Akanksha Dixit, Stephanie Thiebes, Anna-Lena Beerlage et al. Spatial proteomics revealed a CX3CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder Mucosal Immunology 2020-07-01 [PMID: 32112048]
Xiaolong Huang, Jun Wan, Dewen Leng, Yingying Zhang, Shuo Yang Dual‑targeting nanomicelles with CD133 and CD44 aptamers for enhanced delivery of gefitinib to two populations of lung cancer‑initiating cells Experimental and Therapeutic Medicine 2019-11-19 [PMID: 31853290]
M Takehara, Y Sonobe, H Bandou, K Kobayashi, M Nagahama Granulocyte Colony-Stimulating Factor Does Not Influence Clostridium Perfringens α-Toxin-Induced Myonecrosis in Mice Toxins (Basel), 2019-08-30;11(9):. 2019-08-30 [PMID: 31480318] (Neutralization, Mouse)	Neutralization	Mouse
SH Ferguson, DM Foster, B Sherry, ST Magness, DM Nielsen, JL Gookin Interferon-?3 Promotes Epithelial Defense and Barrier Function Against Cryptosporidium parvum Infection Cell Mol Gastroenterol Hepatol, 2019-03-05;0(0):. 2019-03-05 [PMID: 30849550] (Neutralization, Porcine)	Neutralization	Porcine
MJ Lopez, Y Seyed-Raza, A Jamali, DL Harris, P Hamrah The Chemokine Receptor CXCR4 Mediates Recruitment of CD11c+ Conventional Dendritic Cells Into the Inflamed Murine Cornea Invest. Ophthalmol. Vis. Sci., 2018-11-01;59(13):5671-5681. 2018-11-01 [PMID: 30489627] (Isotype Control, Mouse)	Isotype Control	Mouse
Hyung-Geun Moon, Seung-jae Kim, Jong Jin Jeong, Seon-Sook Han, Nizar N. Jarjour, Hyun Lee et al. Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization Immunity 2018-08-01 [PMID: 30054206]
ME Maxson, X Naj, TR O'Meara, JD Plumb, LE Cowen, S Grinstein Integrin-based diffusion barrier separates membrane domains enabling formation of microbiostatic frustrated phagosomes Elife, 2018-03-19;7(0):. 2018-03-19 [PMID: 29553370] (Control, Mouse)	Control	Mouse
M Madsen, PR Hansen, LB Nielsen, RM Cardoso, M van Eck, TX Pedersen Imiquimod-Induced Psoriasis-Like Skin Lesions Do Not Accelerate Atherosclerosis in Low Density Lipoprotein Receptor-Deficient Mice Am. J. Pathol., 2018-03-12;0(0):. 2018-03-12 [PMID: 29545199] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Y Ito, N Schaefer, A Sanchez, D Francisco, R Alam, RJ Martin, JG Ledford, C Stevenson, D Jiang, L Li, M Kraft, HW Chu Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice J Innate Immun, 2018-01-27;0(0):. 2018-01-27 [PMID: 29393212] (Mouse)		Mouse
L Qian, Y Liu, S Wang, W Gong, X Jia, L Liu, F Ye, J Ding, Y Xu, Y Fu, F Tian NKG2D ligand RAE1? induces generation and enhances the inhibitor function of myeloid-derived suppressor cells in mice J. Cell. Mol. Med, 2017-03-09;0(0):. 2017-03-09 [PMID: 28276625] (Neutralization, Mouse)	Neutralization	Mouse
Smooth muscle cell-specific Tgfbr1 deficiency attenuates neointimal hyperplasia but promotes an undesired vascular phenotype for injured arteries Physiol Rep, 2016-12-01;4(23):. 2016-12-01 [PMID: 27923978] (IHC, Mouse)	IHC	Mouse
CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima Nat Immunol, 2016-09-26;0(0):. 2016-09-26 [PMID: 27668800] (Neutralization, Mouse)	Neutralization	Mouse
Marie Madsen, Peter Riis Hansen, Lars Bo Nielsen, Karsten Hartvigsen, Anders Elm Pedersen, Jan Pravsgaard Christensen et al. Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice BMC Dermatology 2016-12-01 [PMID: 27401543]
Kowalewska P, Nguyen U, Burrows L, Fox-Robichaud A Syndecan-1 (CD138) deficiency increases Staphylococcus aureus infection but has no effect on pathology in a mouse model of peritoneal dialysis. J Biomed Sci, 2016-02-01;23(1):20. 2016-02-01 [PMID: 26832929] (IHC-P, Mouse)	IHC-P	Mouse
Sekimoto R, Fukuda S, Maeda N, Tsushima Y, Matsuda K, Mori T, Nakatsuji H, Nishizawa H, Kishida K, Kikuta J, Maijima Y, Funahashi T, Ishii M, Shimomura I Visualized macrophage dynamics and significance of S100A8 in obese fat. Proc Natl Acad Sci U S A, 2015-04-06;112(16):E2058-66. 2015-04-06 [PMID: 25848057] (Mouse)		Mouse
D. Clark Files, Chun Liu, Andrea Pereyra, Zhong-Min Wang, Neil R. Aggarwal, Franco R. D’Alessio et al. Therapeutic exercise attenuates neutrophilic lung injury and skeletal muscle wasting Science Translational Medicine 2015-03-11 [PMID: 25761888]
A. J. Chucair-Elliott, Min Zheng, Daniel J J Carr Degeneration and Regeneration of Corneal Nerves in Response to HSV-1 Infection Investigative Ophthalmology & Visual Science 2015-02-13 [PMID: 25587055]
Thomas M, Buelow B, Nevins A, Jones S, Peterson F, Gundry R, Grayson M, Volkman B Structure-function analysis of CCL28 in the development of post-viral asthma. J Biol Chem, 2015-01-02;290(7):4528-36. 2015-01-02 [PMID: 25556652] (Neutralization, Mouse)	Neutralization	Mouse
Lin Y, Yet S, Hsu Y, Wang G, Hung S Mesenchymal Stem Cells Ameliorate Atherosclerotic Lesions via Restoring Endothelial Function. Stem Cells Transl Med, 2014-12-10;4(1):44-55. 2014-12-10 [PMID: 25504897] (Bioassay, Human)	Bioassay	Human
Francois Malecaze, Dawiyat Massoudi, Pierre Fournie, Cyrielle Tricoire, Myriam Cassagne, Marilyne Malbouyres et al. Upregulation of Bone Morphogenetic Protein-1/Mammalian Tolloid and Procollagen C-Proteinase Enhancer-1 in Corneal Scarring Investigative Ophthalmology & Visual Science 2014-10-24 [PMID: 25249603]
Kowalewska P, Patrick A, Fox-Robichaud A Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation. PLoS ONE, 2014-09-03;9(9):e104537. 2014-09-03 [PMID: 25184228] (IHC-Fr, Mouse)	IHC-Fr	Mouse
Ibrahim O, Dogru M, Matsumoto Y, Igarashi A, Kojima T, Wakamatsu T, Inaba T, Shimizu T, Shimazaki J, Tsubota K Oxidative stress induced age dependent meibomian gland dysfunction in Cu, Zn-superoxide dismutase-1 (Sod1) knockout mice. PLoS ONE, 2014-07-18;9(7):e99328. 2014-07-18 [PMID: 25036096] (IHC, Mouse)	IHC	Mouse
Ellen E Glista-Baker, Alexia J Taylor, Brian C Sayers, Elizabeth A Thompson, James C Bonner Nickel Nanoparticles cause exaggerated lung and airway remodeling in mice lacking the T-box transcription factor, TBX21 (T-bet) Particle and Fibre Toxicology 2014-12-01 [PMID: 24499286]
Weckbach L, Gola A, Winkelmann M, Jakob S, Groesser L, Borgolte J, Pogoda F, Pick R, Pruenster M, Muller-Hocker J, Deindl E, Sperandio M, Walzog B The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via beta2 integrins (CD11/CD18). Blood, 2014-01-23;123(12):1887-96. 2014-01-23 [PMID: 24458438] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Kevin Dhaliwal, Emma Scholefield, David Ferenbach, Michael Gibbons, Rodger Duffin, David A. Dorward et al. Monocytes Control Second-Phase Neutrophil Emigration in Established Lipopolysaccharide-induced Murine Lung Injury American Journal of Respiratory and Critical Care Medicine 2012-09-15 [PMID: 22822022]
Liu H, Liu S, Li Y, Wang X, Xue W, Ge G, Luo X The role of SDF-1-CXCR4/CXCR7 axis in the therapeutic effects of hypoxia-preconditioned mesenchymal stem cells for renal ischemia/reperfusion injury. PLoS ONE, 2012-04-12;7(4):e34608. 2012-04-12 [PMID: 22511954] (Control, Mouse)	Control	Mouse
Oh MH, Oh SY, Yu J IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin. J. Immunol., 2011-05-16;186(12):7232-42. 2011-05-16 [PMID: 21576506] (Control, Mouse)	Control	Mouse
Moore RN, Cherry JF, Mathur V E-cadherin-expressing feeder cells promote neural lineage restriction of human embryonic stem cells. Stem Cells Dev., 2011-06-01;21(1):30-41. 2011-06-01 [PMID: 21469943] (Control, Mouse)	Control	Mouse
Sarra M, Caruso R, Cupi ML, Monteleone I, Stolfi C, Campione E, Diluvio L, Mazzotta A, Botti E, Chimenti S, Costanzo A, MacDonald TT, Pallone F, Monteleone G IL-21 Promotes Skin Recruitment of CD4+ Cells and Drives IFN-{gamma}-Dependent Epidermal Hyperplasia. J. Immunol., 2011-03-25;186(9):5435-42. 2011-03-25 [PMID: 21441456] (Control, Mouse)	Control	Mouse
Heise RL, Stober V, Cheluvaraju C, Hollingsworth JW, Garantziotis S Mechanical Stretch Induces Epithelial-Mesenchymal Transition in Alveolar Epithelia via Hyaluronan Activation of Innate Immunity. J. Biol. Chem., 2011-03-11;286(20):17435-44. 2011-03-11 [PMID: 21398522] (Control, Mouse)	Control	Mouse
Mendez MP, Monroy YK, Du M Overexpression of sICAM-1 in the Alveolar Epithelial Space Results in an Exaggerated Inflammatory Response and Early Death in Gram Negative Pneumonia. Respir. Res., 2011-01-19;12(1):12. 2011-01-19 [PMID: 21247482] (Control, Mouse)	Control	Mouse
Flannagan RS, Harrison RE, Yip CM, Jaqaman K, Grinstein S Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets. J. Cell Biol., 2010-12-06;191(6):1205-18. 2010-12-06 [PMID: 21135140] (Flow Cytometry Control, Mouse)	Flow Cytometry Control	Mouse
Mosconi E, Rekima A, Seitz-Polski B Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development. Mucosal Immunol, 2010-05-19;3(5):461-74. 2010-05-19 [PMID: 20485331] (Control, Mouse)	Control	Mouse
Horvat JC, Starkey MR, Kim RY, Beagley KW, Preston JA, Gibson PG, Foster PS, Hansbro PM Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease. J. Immunol., 2010-03-12;184(8):4159-69. 2010-03-12 [PMID: 20228193] (Control, Mouse)	Control	Mouse
Strasser GA, Kaminker JS, Tessier-Lavigne M Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching. Blood, 2010-02-12;115(24):5102-10. 2010-02-12 [PMID: 20154215] (Control, Mouse)	Control	Mouse
Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat. Med., 2009-08-23;15(9):1016-22. 2009-08-23 [PMID: 19701202] (Control, Mouse)	Control	Mouse
Narasaraju T, Ng HH, Phoon MC MCP-1 antibody treatment enhances damage and impedes repair of the alveolar epithelium in influenza pneumonitis. Am. J. Respir. Cell Mol. Biol., 2009-07-17;42(6):732-43. 2009-07-17 [PMID: 19617401] (Neutralization, Mouse)	Neutralization	Mouse
Haraguchi G, Suzuki J, Kosuge H, Ogawa M, Koga N, Muto S, Itai A, Kagechika H, Shudo K, Isobe M A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model. J. Mol. Cell. Cardiol., 2006-09-11;41(5):885-92. 2006-09-11 [PMID: 16963076] (Control, Mouse)	Control	Mouse
Chen L, Lin SX, Agha-Majzoub R, Overbergh L, Mathieu C, Chan LS CCL27 is a critical factor for the development of atopic dermatitis in the keratin-14 IL-4 transgenic mouse model. Int. Immunol., 2006-05-30;18(8):1233-42. 2006-05-30 [PMID: 16735375] (Control, Mouse)	Control	Mouse
Mendez MP, Morris SB, Wilcoxen S, Greeson E, Moore B, Paine R Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury. Am. J. Physiol. Lung Cell Mol. Physiol., 2005-12-22;290(5):L962-70. 2005-12-22 [PMID: 16373671] (Control, Mouse)	Control	Mouse
Jeyaseelan S, Chu HW, Young SK, Worthen GS Transcriptional profiling of lipopolysaccharide-induced acute lung injury. Infect. Immun., 2004-12-01;72(12):7247-56. 2004-12-01 [PMID: 15557650] (Control, Neutralization, Mouse)	Control, Neutralization	Mouse
Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation. J. Immunol., 2001-01-15;166(2):1233-40. 2001-01-15 [PMID: 11145706] (Control, Mouse)	Control	Mouse
Show All 56 Publications. Collapse Publications.

Array MAB0061

• IgG2b Antibodies
• IgG2b ELISA Kits
• IgG2b Isotype Controls
• IgG2b Antibodies