Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified
Alternate Names for Histamine H1R Antibody
H1R
H1-R
hisH1
Histamine H1 R
Histamine H1R
histamine receptor H1
HRH1
subclass H1
Background
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Itsvarious actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless untilrecently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupledreceptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due tocontraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in thecentral nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.(provided by RefSeq)
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for Histamine H1R Antibody (NB600-795). (Showing 1 - 1 of 1 FAQs).
I would like to know if HRH1 antibody (NB600-795) and HRH3 antibody (NBP1-71095) have cross-reactivity with mouse or whether the reactivity is only predicted? I'd like to test for presence of these receptors in our mouse neural stem cells.
For NB600-795, I am showing the reactivity of Mouse, Rat, Dog, and Cow are based upon homology, but will still be guaranteed by us since they are shown on the datasheet. Therefore if it does not work in your mouse samples for this one we would be happy to send you a replacement or refund. The second antibody NBP1-71095 was also determined to have Rat and Mouse reactivity based on sequence homology, but like the first will be guaranteed for the applications listed for those species.
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